Title : Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.

Pub. Date : 2011 Jan

PMID : 21106878






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1 Lipophilic pyruvate derivatives and antioxidants show promise at rescuing mTOR activity and muscle protein synthesis by maintaining IGF-I sensitivity in this model. Pyruvic Acid mechanistic target of rapamycin kinase Homo sapiens