Title : In vivo probes of drug transport: commonly used probe drugs to assess function of intestinal P-glycoprotein (ABCB1) in humans.

Pub. Date : 2011

PMID : 21103977






1 Functional Relationships(s)
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1 Digoxin and talinolol are suitable in vivo probe drugs for intestinal P-gp under the precondition, that they are used as tools in carefully designed pharmacokinetic studies with adequate biometrically planning of the sample size and that several limitations are considered in interpreting and discussion of the study results. Digoxin ATP binding cassette subfamily B member 1 Homo sapiens