Pub. Date : 2011 Feb
PMID : 21092747
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons. | polyglutamine | transformation related protein 53, pseudogene | Mus musculus |
| 2 | Our results suggest that polyglutamine-expanded ataxin-3 upregulates mRNA expression of Bax and PUMA and causes apoptotic death of affected neurons by enhancing phosphorylation and transcriptional activity of p53. | polyglutamine | transformation related protein 53, pseudogene | Mus musculus |