Title : Structure-based design, synthesis, and pharmacological evaluation of 3-(aminoalkyl)-5-fluoroindoles as myeloperoxidase inhibitors.

Pub. Date : 2010 Dec 23

PMID : 21090682






1 Functional Relationships(s)
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1 In vitro assays were used to study the effects of these compounds on the inhibition of MPO-mediated taurine chlorination and oxidation of LDLs. Taurine myeloperoxidase Homo sapiens