Title : Assessment of the pharmacokinetic interaction between the novel DPP-4 inhibitor linagliptin and a sulfonylurea, glyburide, in healthy subjects.

Pub. Date : 2011

PMID : 21084763






1 Functional Relationships(s)
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1 The aim of this study was to investigate the effect of the dipeptidyl peptidase-4 inhibitor linagliptin on the pharmacokinetics of glyburide (a CYP2C9 and CYP3A4 substrate) and vice versa. Linagliptin cytochrome P450 family 3 subfamily A member 4 Homo sapiens