Pub. Date : 2011 Aug
PMID : 21080015
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We used the docking method to explore possible binding modes of an entry inhibitor (maraviroc) and non-nucleoside reverse transcriptase inhibitors (delavirdine, efavirenz and etravirine) to cytochrome P450 3A4 (CYP3A4). | efavirenz | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | We used the docking method to explore possible binding modes of an entry inhibitor (maraviroc) and non-nucleoside reverse transcriptase inhibitors (delavirdine, efavirenz and etravirine) to cytochrome P450 3A4 (CYP3A4). | efavirenz | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | We observed that efavirenz and etravirine induce metabolism of co-administered drugs by binding to a unique position in the active site of CYP3A4. | efavirenz | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |