Pub. Date : 2011 Jan
PMID : 21077177
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, the reduction of Cu/Zn-SOD and the induction of Mn-SOD by TPA in leukemic cells have been reported; however, the regulation of EC-SOD by TPA remains poorly understood. | Tetradecanoylphorbol Acetate | superoxide dismutase 3 | Homo sapiens |
| 2 | Here, we explored the regulation of EC-SOD during the monocytic differentiation of U937 cells by TPA. | Tetradecanoylphorbol Acetate | superoxide dismutase 3 | Homo sapiens |
| 3 | Overall, our results suggest that the expression of EC-SOD is decreased by TPA through intracellular signaling consisting of PKC, NOX-derived ROS and MEK/ERK, but not of NF-kappaB signaling. | Tetradecanoylphorbol Acetate | superoxide dismutase 3 | Homo sapiens |