Pub. Date : 1990 Mar
PMID : 2107492
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 2-Aminopurine abolishes EGF- and TPA-stimulated pp33 phosphorylation and c-fos induction without affecting the activation of protein kinase C. Epidermal Growth Factor (EGF) and Tetradecanoyl Phorbol Acetate (TPA) initiate signalling cascades in C3H 10T1/2 fibroblasts by primarily activating distinct protein kinases, the EGF receptor tyrosine kinase and protein kinase C respectively; there is no signal crossover at the initiation of signalling. | Tetradecanoylphorbol Acetate | ret proto-oncogene | Homo sapiens |