Title : Optimization of cell-based assays to quantify the anti-inflammatory/allergic potential of test substances in 96-well format.

Pub. Date : 2011 Jun

PMID : 21069571






1 Functional Relationships(s)
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1 Dexamethasone attenuated LPS-induced IL-1 beta (IC(50) = 70 nM), IL-6 (IC(50) = 58 nM) and TNF-alpha (IC(50) = 44 nM) release, whereas celecoxib, a specific COX-2 inhibitor showed marked reduction in LPS-induced PGE(2) (IC(50) = 23 nM) production. Dexamethasone interleukin 6 Homo sapiens