Title : A role for protein kinase C in the regulation of membrane fluidity and Ca²(+) flux at the endoplasmic reticulum and plasma membranes of HEK293 and Jurkat cells.

Pub. Date : 2011 Feb

PMID : 21062642






6 Functional Relationships(s)
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1 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens
2 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens
3 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens
4 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens
5 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens
6 In HEK293 and Jurkat cells, the Ca2(+) release and Ca2(+) uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition with Go6983 or knockdown of PKCalpha or PKCbeta using shRNA. Tetradecanoylphorbol Acetate protein kinase C alpha Homo sapiens