Title : Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model.

Pub. Date : 2011 Feb

PMID : 21056987






1 Functional Relationships(s)
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1 This information may be important for understanding paclitaxel metabolism in vivo and in the investigation of the role of genetic polymorphisms in the metabolizing enzymes CYP2C8 and CYP3A4/CYP3A5 and the ABCB1 transporter. Paclitaxel cytochrome P450 family 3 subfamily A member 4 Homo sapiens