Pub. Date : 1995
PMID : 21043585
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | C-myc expression was turned off by TPA (16 nM) stimulation of cells within 2-4 h. This TPA-mediated effect likely occurred at the transcriptional level since the half life of c-myc mRN A induced by GM-CSF was less than 30 min. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | C-myc expression was turned off by TPA (16 nM) stimulation of cells within 2-4 h. This TPA-mediated effect likely occurred at the transcriptional level since the half life of c-myc mRN A induced by GM-CSF was less than 30 min. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | C-myc expression was turned off by TPA (16 nM) stimulation of cells within 2-4 h. This TPA-mediated effect likely occurred at the transcriptional level since the half life of c-myc mRN A induced by GM-CSF was less than 30 min. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | C-myc expression was turned off by TPA (16 nM) stimulation of cells within 2-4 h. This TPA-mediated effect likely occurred at the transcriptional level since the half life of c-myc mRN A induced by GM-CSF was less than 30 min. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 5 | These studies suggest a link between PKC stimulation by TPA and AP-1 activation with downregulation of c-myc transcription on a molecular level. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |