Title : Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing's sarcoma cells.

Pub. Date : 2010 Oct

PMID : 21036715






7 Functional Relationships(s)
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1 Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing"s sarcoma cells. Curcumin tumor protein p53 Homo sapiens
2 Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing"s sarcoma cells. Curcumin tumor protein p53 Homo sapiens
3 AIM: Curcumin has been demonstrated to have antitumor effects including radiosensitization by modulating many molecular targets including p53. Curcumin tumor protein p53 Homo sapiens
4 Herein, we investigated the radiosensitizing effect of curcumin in p53 mutant Ewing"s sarcoma (ES) cells. Curcumin tumor protein p53 Homo sapiens
5 CONCLUSION: These results suggest that curcumin potentially radiosensitizes p53-mutant ES cells by regulating IR-modulated p53-response genes. Curcumin tumor protein p53 Homo sapiens
6 CONCLUSION: These results suggest that curcumin potentially radiosensitizes p53-mutant ES cells by regulating IR-modulated p53-response genes. Curcumin tumor protein p53 Homo sapiens
7 However, the curcumin-associated p53-independent regulation of downstream targets remains to be explored. Curcumin tumor protein p53 Homo sapiens