Title : [Effect of lovastatin and rosiglitazone on cholesterol reverse transportation in foam cell].

Pub. Date : 2010 Aug

PMID : 20979792






2 Functional Relationships(s)
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1 OBJECTIVES: This study was designed to explore the function of ATP binding cassette transporter 1 (ABCA1) and Apolipoprotein A-I (ApoA-I) in cholesterol reverse transportation (RCT), the influence of lovastatin and rosiglitazone on the concentration of cholesterol (CHO) in THP-1 (human monocytic leukemia cell line) derived foam cells. Lovastatin ATP binding cassette subfamily A member 1 Homo sapiens
2 The effect of lovastatin and rosiglitazone on ABCA1 protein expression in THP-1 cell line derived macrophage were detected by western blot. Lovastatin ATP binding cassette subfamily A member 1 Homo sapiens