Title : von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas.

Pub. Date : 2010 Nov 1

PMID : 20978146






1 Functional Relationships(s)
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1 PURPOSE: We have previously shown that von Hippel-Lindau (VHL) regulates ubiquitylation and proline 1465 hydroxylation of the large subunit of RNA polymerase II, Rpb1, in human renal clear cell carcinoma (RCC) cell lines. Proline von Hippel-Lindau tumor suppressor Homo sapiens