Title : Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro.

Pub. Date : 2010 Oct 26

PMID : 20977754






2 Functional Relationships(s)
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1 In addition, treatment with propranolol decreased the level of NF-kappaB and, subsequently, down-regulated VEGF, COX-2, and EGFR expression. Propranolol vascular endothelial growth factor A Homo sapiens
2 CONCLUSIONS: Taken together, these results suggested that propranolol enhanced the sensitivity of gastric cancer cells to radiation through the inhibition of beta-ARs and the downstream NF-kappaB-VEGF/EGFR/COX-2 pathway. Propranolol vascular endothelial growth factor A Homo sapiens