Title : Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy.

Pub. Date : 2010 Dec

PMID : 20977674






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Dentatorubral-pallidoluysian atrophy is caused by polyglutamine (polyQ) expansion in atrophin-1 (ATN1). polyglutamine atrophin 1 Mus musculus
2 Dentatorubral-pallidoluysian atrophy is caused by polyglutamine (polyQ) expansion in atrophin-1 (ATN1). polyglutamine atrophin 1 Mus musculus
3 Recent studies have shown that nuclear accumulation of ATN1 and cleaved fragments with expanded polyQ is the pathological process underlying neurodegeneration in dentatorubral-pallidoluysian atrophy. polyglutamine atrophin 1 Mus musculus