Title : Structural relationship between the active sites of β-lactam-recognizing and amidase signature enzymes: convergent evolution?

Pub. Date : 2010 Nov 16

PMID : 20977193






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The active site of this superfamily of enzymes includes a Ser1/Ser2(Tyr)/Lys1(His)/Lys2 tetrad in which Ser1 is a nucleophilic catalyst that becomes acylated in the formation of an acyl-enzyme intermediate. Tyrosine jagged canonical Notch ligand 2 Homo sapiens