Title : Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells.

Pub. Date : 2010 Dec 18

PMID : 20970436






1 Functional Relationships(s)
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1 KEY FINDINGS: Pa led to cytotoxicity and apoptosis in HepG2 cells in a dose-dependent pattern and also induced ER stress indicated by increased phosphorylation of eIF2alpha, upregulation of IRE1alpha and CHOP. Palmitates DNA damage inducible transcript 3 Homo sapiens