Title : Reprint of: Catestatin: a multifunctional peptide from chromogranin A.

Pub. Date : 2010 Nov 30

PMID : 20965217






2 Functional Relationships(s)
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1 In 1997, we identified a novel peptide, catestatin (CST: bovine chromogranin A [CHGA]344-364: RSMRLSFRARGYGFRGPGLQL; human CHGA352-372: SSMKLSFRARGYGFRGPGPQL), which is a potent inhibitor of nicotinic-cholinergic-stimulated catecholamine secretion. Catecholamines cystatin 12, pseudogene Homo sapiens
2 Utilizing systematic polymorphism discovery at the human CHGA locus we discovered three human variants of CST: G364S, P370L, and R374Q that showed differential potencies towards the inhibition of catecholamine secretion. Catecholamines cystatin 12, pseudogene Homo sapiens