Pub. Date : 2010 Nov 30
PMID : 20965217
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In 1997, we identified a novel peptide, catestatin (CST: bovine chromogranin A [CHGA]344-364: RSMRLSFRARGYGFRGPGLQL; human CHGA352-372: SSMKLSFRARGYGFRGPGPQL), which is a potent inhibitor of nicotinic-cholinergic-stimulated catecholamine secretion. | Catecholamines | cystatin 12, pseudogene | Homo sapiens |
2 | Utilizing systematic polymorphism discovery at the human CHGA locus we discovered three human variants of CST: G364S, P370L, and R374Q that showed differential potencies towards the inhibition of catecholamine secretion. | Catecholamines | cystatin 12, pseudogene | Homo sapiens |