Title : TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.

Pub. Date : 2010 Nov

PMID : 20957750






1 Functional Relationships(s)
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1 Our findings offer a new mechanistic insight into TLR3/TRIF signalling through a hitherto unknown mechanism whereby Mal inhibits poly(I:C)-induced IRF7 activation and concomitant IFN-beta production. Poly I-C interferon beta 1 Homo sapiens