Pub. Date : 2011 Feb
PMID : 20954832
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ex vivo studies revealed that GSH and NAC effectively scavenged N-chloramines in sputum and inhibited sputum MPO activity with potency exquisitely dependent upon MPO activity levels. | Glutathione | myeloperoxidase | Homo sapiens |
| 2 | Ex vivo studies revealed that GSH and NAC effectively scavenged N-chloramines in sputum and inhibited sputum MPO activity with potency exquisitely dependent upon MPO activity levels. | Glutathione | myeloperoxidase | Homo sapiens |
| 3 | Detailed kinetic analyses revealed that NAC and GSH inhibit MPO by distinct mechanisms. | Glutathione | myeloperoxidase | Homo sapiens |
| 4 | The findings reveal that MPO activity and its reactive products represent useful predictors of the doses of inhaled thiol antioxidants required to ameliorate airway oxidative stress and inflammation in CF patients and provide mechanistic insight into the antioxidative/anti-inflammatory mechanisms of action of GSH and NAC when administered into the CF lung. | Glutathione | myeloperoxidase | Homo sapiens |