Title : A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.

Pub. Date : 2011 Jan 20

PMID : 20946921






1 Functional Relationships(s)
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1 Its efficacy was further increased by simvastatin, which up-regulates the LDLR levels and contemporarily reduces the Pgp activity, thus increasing the liposomes uptake and limiting the drug efflux. Simvastatin low density lipoprotein receptor Homo sapiens