Title : N-terminal and C-terminal heparin-binding domain polypeptides derived from fibronectin reduce adhesion and invasion of liver cancer cells.

Pub. Date : 2010 Oct 13

PMID : 20939933






1 Functional Relationships(s)
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1 Polypeptides rhFNHN29 and rhFNHC36 abrogated the tyrosine phosphorylation of focal adhesion kinase (p-FAK) and activation of activator protein 1 (AP-1), resulting in the decrease of integrin alphav, beta3 and beta1 expression as well as the reduction of MMP-9 activity. Tyrosine integrin subunit alpha V Homo sapiens