Pub. Date : 2010 Sep
PMID : 20936727
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effects of simvastatin on expression of CTGF and alpha-SMA in renal tubulointerstitium of rats with diabetic nephropathy]. | Simvastatin | cellular communication network factor 2 | Rattus norvegicus |
| 2 | OBJECTIVE: To investigate the effects of low-dose simvastatin on the expression of connective tissue growth factor (CTGF) and alpha-smooth muscle actin (alpha-SMA) in the renal tubulointerstitium of rats with diabetic nephropathy. | Simvastatin | cellular communication network factor 2 | Rattus norvegicus |
| 3 | OBJECTIVE: To investigate the effects of low-dose simvastatin on the expression of connective tissue growth factor (CTGF) and alpha-smooth muscle actin (alpha-SMA) in the renal tubulointerstitium of rats with diabetic nephropathy. | Simvastatin | cellular communication network factor 2 | Rattus norvegicus |
| 4 | CONCLUSION: Simvastatin with a under cholesterol-lowering dose, can decrease the expression levels of CTGF and alpha-SMA in renal tubulointerstitium of rats with diabetic nephropathy, by which the progression of the tubulointerstitial fibrosis would be delayed. | Simvastatin | cellular communication network factor 2 | Rattus norvegicus |