Title : Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.

Pub. Date : 2011 Jan 1

PMID : 20932985






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-alpha via distinct NF-kappaB pathways in human nasal epithelial cells. poly C-X-C motif chemokine ligand 8 Homo sapiens
2 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. poly C-X-C motif chemokine ligand 8 Homo sapiens