Pub. Date : 2010 Nov
PMID : 20932931
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | cPA is a specific, high-affinity antagonist of peroxisome proliferator-activated receptor gamma (PPARgamma); however, the molecular mechanism by which cPA inhibits cellular proliferation remains to be clarified. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 2 | cPA is a specific, high-affinity antagonist of peroxisome proliferator-activated receptor gamma (PPARgamma); however, the molecular mechanism by which cPA inhibits cellular proliferation remains to be clarified. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 3 | cPA suppressed cell growth, and this effect was reversed by the addition of a PPARgamma agonist. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 4 | These results indicate that the physiological effects of cPA are partly due to PPARgamma inhibition. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 5 | Our results identify PPARgamma as a molecular mediator of cPA activity in HT-29 cells, and suggest that cPA and the PPARgamma pathway might be therapeutic targets in the treatment of colon cancer. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 6 | Our results identify PPARgamma as a molecular mediator of cPA activity in HT-29 cells, and suggest that cPA and the PPARgamma pathway might be therapeutic targets in the treatment of colon cancer. | cpa | peroxisome proliferator activated receptor gamma | Homo sapiens |