Title : Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.

Pub. Date : 2011 Jan

PMID : 20931131






1 Functional Relationships(s)
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1 The effect of this compound was dramatically increased when used in combination with chemotherapeutic drug and/or the HDAC inhibitor Trichostatin A, confirming a proposed synergistic mechanism of p53 deacetylation by SIRT1 and Type I/II HDACs. trichostatin A tumor protein p53 Homo sapiens