Title : Characterization of proliferative effects of insulin, insulin analogues and insulin-like growth factor-1 (IGF-1) in human lung fibroblasts.

Pub. Date : 2010 Dec

PMID : 20924562






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Insulin and IGF-1 stimulated [(3)H]-thymidine incorporation in all cells. Thymidine insulin Homo sapiens
2 Insulin-induced stimulation of [(3)H]-thymidine incorporation was reduced by 83% after siRNA-mediated down-regulation of IGF-1 receptor by about 75%, but not affected by a similar down-regulation of the insulin receptor. Thymidine insulin Homo sapiens