Title : Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids.

Pub. Date : 2010 Dec 17

PMID : 20921226






1 Functional Relationships(s)
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1 Indeed, we found that high concentrations of hydroperoxide activator (e.g. 65 muM) overcame a prolonged lag phase (>1 h) and unveiled a dioxygenase activity with arachidonic acid; the main products were the 5-, 9-, and 7-hydroperoxyeicosatetraenoic acids (HPETEs). Hydrogen Peroxide latexin Homo sapiens