Pub. Date : 1990 Sep
PMID : 2091733
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | All the azole antifungals inhibit the cytochrome P450-dependent, 14 alpha-demethylase, a key enzyme in the synthesis of ergosterol, the main sterol in most fungal cells. | Azoles | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Of all the azoles tested, itraconazole shows the highest affinity for the cytochrome P450 involved. | Azoles | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |