Title : Quantitative insulin and C-peptide levels among ED patients with sulfonylurea-induced hypoglycemia-a prospective case series.

Pub. Date : 2010 Oct

PMID : 20887914






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1 Quantitative insulin and C-peptide levels among ED patients with sulfonylurea-induced hypoglycemia-a prospective case series. Sulfonylurea Compounds insulin Homo sapiens
2 Quantitative insulin and C-peptide levels among ED patients with sulfonylurea-induced hypoglycemia-a prospective case series. Sulfonylurea Compounds insulin Homo sapiens
3 A recently published systematic review of 22 articles involving 76 patients with sulfonylurea-induced hypoglycemia (glucose <49 mg/dL) resulting from accidental ingestion or intentional overdose found that patients had an average serum insulin concentration of 3.9 muIU/mL or higher and an average serum C-peptide concentration of 1.4 ng/mL or higher. Sulfonylurea Compounds insulin Homo sapiens
4 A recently published systematic review of 22 articles involving 76 patients with sulfonylurea-induced hypoglycemia (glucose <49 mg/dL) resulting from accidental ingestion or intentional overdose found that patients had an average serum insulin concentration of 3.9 muIU/mL or higher and an average serum C-peptide concentration of 1.4 ng/mL or higher. Sulfonylurea Compounds insulin Homo sapiens
5 RESULTS: Thirteen of 14 study subjects had initial insulin and C-peptide levels consistent with the diagnosis of sulfonylurea-induced hypoglycemia as previously defined among patients presenting after overdose. Sulfonylurea Compounds insulin Homo sapiens
6 CONCLUSION: Patients presenting with hypoglycemia resulting from therapeutic sulfonylurea use demonstrate similar insulin and C-peptide levels as has previously been published among patients who presented with presumed overdose. Sulfonylurea Compounds insulin Homo sapiens
7 CONCLUSION: Patients presenting with hypoglycemia resulting from therapeutic sulfonylurea use demonstrate similar insulin and C-peptide levels as has previously been published among patients who presented with presumed overdose. Sulfonylurea Compounds insulin Homo sapiens