Pub. Date : 2010 Dec 15
PMID : 20883688
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9. | Hesperidin | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 2 | The purpose of this study is to evaluate the effect of hesperidin in modulating the expressions of cyclooxygenase-2 (COX-2), mast cells (MCs) and matrix metalloproteinases (MMPs) during benzo(a)pyrene (B(a)P) induced lung carcinogenesis in mice. | Hesperidin | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 3 | The purpose of this study is to evaluate the effect of hesperidin in modulating the expressions of cyclooxygenase-2 (COX-2), mast cells (MCs) and matrix metalloproteinases (MMPs) during benzo(a)pyrene (B(a)P) induced lung carcinogenesis in mice. | Hesperidin | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 4 | Supplementation of hesperidin (25 mg/kg body weight) to lung cancer bearing mice attenuated MCD and downregulated the expressions of COX-2, MMP-2 and MMP-9. | Hesperidin | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 5 | These observations show that hesperidin exerts its anti-carcinogenic activity against lung cancer by altering the expressions of COX-2, MMP-2 and MMP-9. | Hesperidin | prostaglandin-endoperoxide synthase 2 | Mus musculus |