Title : Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.

Pub. Date : 2010 Nov 26

PMID : 20876579






1 Functional Relationships(s)
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1 Stimulated IDE secretion and Abeta degradation were also observed in blood of mice upon peripheral treatment with lovastatin. Lovastatin amyloid beta (A4) precursor protein Mus musculus