Pub. Date : 2011 Apr
PMID : 20875690
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Antimycotics itraconazole and terbinafine hydrochloride increased hBD-3 secretion and mRNA levels in parallel to the enhanced activity of activator protein-1, expression and phosphorylation of activator protein-1 component, c-Fos, but fluconazole was ineffective. | Itraconazole | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
2 | Antimycotics itraconazole and terbinafine hydrochloride increased hBD-3 secretion and mRNA levels in parallel to the enhanced activity of activator protein-1, expression and phosphorylation of activator protein-1 component, c-Fos, but fluconazole was ineffective. | Itraconazole | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
3 | Antimycotics itraconazole and terbinafine hydrochloride increased hBD-3 secretion and mRNA levels in parallel to the enhanced activity of activator protein-1, expression and phosphorylation of activator protein-1 component, c-Fos, but fluconazole was ineffective. | Itraconazole | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
4 | These results suggest that itraconazole and terbinafine hydrochloride may enhance c-Fos expression and phosphorylation, activator protein-1 activity and hBD-3 production by increasing prostaglandin D(2) release from keratinocytes. | Itraconazole | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
5 | These results suggest that itraconazole and terbinafine hydrochloride may enhance c-Fos expression and phosphorylation, activator protein-1 activity and hBD-3 production by increasing prostaglandin D(2) release from keratinocytes. | Itraconazole | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |