Pub. Date : 2011 Jun
PMID : 20868701
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In WT mice in which minocycline inhibited development of cocaine sensitization, a 4-day cocaine treatment increased GluR1 phosphorylation at both Ser831 and Ser845 sites in the frontal cortex but not the striatum; further, this effect was prevented by minocycline. | Cocaine | glutamate receptor, ionotropic, AMPA1 (alpha 1) | Mus musculus |
| 2 | Under basal conditions and in response to a single cocaine injection the levels of GluR1, GluR2, and GluR3 AMPA receptor subunits did not differ between WT and 5-LOX-deficient mice, but the response of GluR1 phosphorylation to a single cocaine injection was greater under the 5-LOX deficiency. | Cocaine | glutamate receptor, ionotropic, AMPA1 (alpha 1) | Mus musculus |