Title : Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds.

Pub. Date : 2011

PMID : 20859794






1 Functional Relationships(s)
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1 All known PDE inhibitors contain one or more rings that mimic the purine in the cN substrate and directly compete with cN for access to the catalytic site; this review focuses on inhibitors that contain a nucleus that is closely related to the xanthine ring of theophylline and caffeine and the purine ring of cNs. Theophylline aldehyde dehydrogenase 7 family member A1 Homo sapiens