Pub. Date : 2011 Jan
PMID : 20857093
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. | Oxycodone | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | PURPOSE: The main metabolic pathways of oxycodone, a potent opioid analgetic, are N-demethylation (CYP3A4) to inactive noroxycodone and O-demethylation (CYP2D6) to active oxymorphone. | Oxycodone | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |