Title : Mechanism of low-frequency ultrasound in opening blood-tumor barrier by tight junction.

Pub. Date : 2011 Mar

PMID : 20852968






2 Functional Relationships(s)
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1 The mRNA and protein expression levels of claudin-5, occludin, and ZO-1 decreased significantly at 3 h, restored gradually and nearly recovered after 12 h. The correlation between the increase of BTB permeability and the reduction of tight junction-related proteins suggests that LFU combined with microbubbles may be involved in the opening of the BTB by the tight junction-related proteins. btb tight junction protein 1 Homo sapiens
2 The mRNA and protein expression levels of claudin-5, occludin, and ZO-1 decreased significantly at 3 h, restored gradually and nearly recovered after 12 h. The correlation between the increase of BTB permeability and the reduction of tight junction-related proteins suggests that LFU combined with microbubbles may be involved in the opening of the BTB by the tight junction-related proteins. btb tight junction protein 1 Homo sapiens