Title : Identification of Escherichia coli mismatch-specific uracil DNA glycosylase as a robust xanthine DNA glycosylase.

Pub. Date : 2010 Dec 31

PMID : 20852254






1 Functional Relationships(s)
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1 Molecular modeling and molecular dynamics simulations reveal distinct hydrogen-bonding patterns in the active site of E. coli MUG that account for the specificity differences between E. coli MUG and human thymine DNA glycosylase as well as that between the wild type MUG and the Asn-140 and Ser-23 mutants. Hydrogen thymine DNA glycosylase Homo sapiens