Pub. Date : 2011 Jan 10
PMID : 20851742
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF. | Simvastatin | glial cell derived neurotrophic factor | Rattus norvegicus |
2 | Results show that the simvastatin-treated animals showed significantly better locomotor function recovery, better electrophysiological outcome, less myelin loss, and higher expression of BDNF and GDNF. | Simvastatin | glial cell derived neurotrophic factor | Rattus norvegicus |
3 | These findings suggest that simvastatin treatment starting 1 day after SCI can significantly improve locomotor recovery, and this neuroprotective effect may be related to the upregulation of BDNF and GDNF. | Simvastatin | glial cell derived neurotrophic factor | Rattus norvegicus |