Title : Metabolism and action of proteasome inhibitors in primary human hepatocytes.

Pub. Date : 2010 Dec

PMID : 20837660






1 Functional Relationships(s)
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1 The efficacy of MG132 was increased by inclusion of ketoconazole in the hepatocyte incubations and decreased by prior treatment of the cultures with the CYP3A inducers phenobarbital or rifampicin. Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens