Title : Mercury modulates the CYP1A1 at transcriptional and posttranslational levels in human hepatoma HepG2 cells.

Pub. Date : 2010 Dec 15

PMID : 20837117






1 Functional Relationships(s)
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1 Importantly, Hg(2+) increased the expression of heme oxygenase-1 (HO-1), a rate limiting enzyme in heme degradation, which coincided with further decrease in the CYP1A1 catalytic activity levels. Heme heme oxygenase 1 Homo sapiens