Title : Dexamethasone enhances ATP-induced inflammatory responses in endothelial cells.

Pub. Date : 2010 Dec

PMID : 20826566






2 Functional Relationships(s)
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1 When cells were pretreated with dexamethasone, a prototypic glucocorticoid, ATP-induced IL-6 production was enhanced in a time- and dose-dependent manner. Dexamethasone interleukin 6 Homo sapiens
2 Cells treated with dexamethasone induced mRNA expression of the purinergic P2Y(2) receptor (P2Y(2)R) 1.8- +- 0.1-fold and, when stimulated with ATP, enhanced Ca(2+) release and augmented IL-6 mRNA expression. Dexamethasone interleukin 6 Homo sapiens