Pub. Date : 2011 Aug
PMID : 20821348
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Results from chromatin immunoprecipitation experiments showed that bexarotene treatment causes the recruitment of DEC2 and HDAC1 (histone deacetylase 1) to the cyclin D1 promoter. | Bexarotene | histone deacetylase 1 | Homo sapiens |
| 2 | Results from chromatin immunoprecipitation experiments showed that bexarotene treatment causes the recruitment of DEC2 and HDAC1 (histone deacetylase 1) to the cyclin D1 promoter. | Bexarotene | histone deacetylase 1 | Homo sapiens |
| 3 | These results suggest that bexarotene down-regulates cyclin D1 through induction of DEC2, followed by recruitment of HDAC1 to the cyclin D1 promoter causing transcriptional repression. | Bexarotene | histone deacetylase 1 | Homo sapiens |