Title : Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry.

Pub. Date : 2011 Jan 5

PMID : 20817448






1 Functional Relationships(s)
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1 Because cyclooxygenases (COX) convert arachidonic acid into pro-inflammatory cyclic endoperoxides, inhibition of these enzymes and especially the inducible COX-2 form is an important therapeutic approach to manage inflammatory diseases and possibly prevent cancer. Arachidonic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens