Pub. Date : 2010 Nov 1
PMID : 20814245
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer. | cyclopamine | GLI family zinc finger 3 | Homo sapiens |
| 2 | Regression analysis revealed that GLI3 expression significantly correlated with cyclopamine resistance (r = 0.80; p = 0.0102). | cyclopamine | GLI family zinc finger 3 | Homo sapiens |
| 3 | Knockdown of GLI3 using siRNAs increased sensitivity to cyclopamine. | cyclopamine | GLI family zinc finger 3 | Homo sapiens |
| 4 | These data suggest that Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer. | cyclopamine | GLI family zinc finger 3 | Homo sapiens |