Title : Andrographolide and 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines.

Pub. Date : 2010 Nov 11

PMID : 20813180






3 Functional Relationships(s)
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1 RESULTS: Our data suggest that addition of compounds AP1 or AP2 reduces the phenotypes indicating diabetic nephropathy in MES-13 cells. 2-(N-morpholino)ethanesulfonic acid jun proto-oncogene Mus musculus
2 Furthermore, AP1 and AP2 do not have antioxidant ability in acellular environment; however, addition of AP1 and AP2 reduced intracellular oxidative states in high glucose cultured MES-13 cells. 2-(N-morpholino)ethanesulfonic acid jun proto-oncogene Mus musculus
3 Furthermore, AP1 and AP2 do not have antioxidant ability in acellular environment; however, addition of AP1 and AP2 reduced intracellular oxidative states in high glucose cultured MES-13 cells. 2-(N-morpholino)ethanesulfonic acid jun proto-oncogene Mus musculus