Title : ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos.

Pub. Date : 2010 Oct

PMID : 20810156






3 Functional Relationships(s)
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Protein Name
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1 ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. Leukotrienes leukotriene A4 hydrolase Homo sapiens
2 OBJECTIVE: To identify modulating effects of arachidonate 5-lipoxygenase-activating protein (ALOX5AP) and leukotriene A(4) hydrolase (LTA4H) gene polymorphisms on the drug-drug interaction between leukotriene modifiers and albuterol in Mexicans and Puerto Ricans. Leukotrienes leukotriene A4 hydrolase Homo sapiens
3 CONCLUSION: LTA4H and ALOX5AP gene polymorphisms modify the augmentation of bronchodilator responsiveness by leukotriene modifiers in Puerto Ricans but not Mexicans with asthma. Leukotrienes leukotriene A4 hydrolase Homo sapiens