Title : Effect of fluvastatin, lovastatin, nifedipine and verapamil on the systemic exposure of nateglinide in rabbits.

Pub. Date : 2010 Nov

PMID : 20809476






2 Functional Relationships(s)
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1 Fluvastatin and nifedipine increased the systemic exposure of nateglinide in rabbits, probably due to their inhibitory action on the metabolism of nateglinide by CYP2C5 (human CYP2C9). Nateglinide cytochrome P450 2C5 Oryctolagus cuniculus
2 Fluvastatin and nifedipine increased the systemic exposure of nateglinide in rabbits, probably due to their inhibitory action on the metabolism of nateglinide by CYP2C5 (human CYP2C9). Nateglinide cytochrome P450 2C5 Oryctolagus cuniculus